1,7-Naphthyridine, 5,6,7,8-tetrahydro-

1,7-Naphthyridine, 5,6,7,8-tetrahydro- - Names and Identifiers

Name	5,6,7,8-TETRAHYDRO-[1,7]NAPHTHYRIDINE
Synonyms	5,6,7,8-Tetrahydro-1,7phthyridine 5,6,7,8-Tetrahydro-1,7-naphthyridine 5,6,7,8-Tetrahydro[[1,7]-naphthyridin 5,6,7,8-TETRAHYDRO-[1,7]NAPHTHYRIDINE 1,7-Naphthyridine, 5,6,7,8-tetrahydro- 1,7-naphthyridine, 5,6,7,8-tetrahydro-
CAS	13623-85-3
EINECS	604-604-1
InChI	InChI=1/C8H10N2/c1-2-7-3-5-9-6-8(7)10-4-1/h1-2,4,9H,3,5-6H2

1,7-Naphthyridine, 5,6,7,8-tetrahydro- - Physico-chemical Properties

Molecular Formula	C8H10N2
Molar Mass	134.18
Density	1.068±0.06 g/cm3(Predicted)
Melting Point	275 °C(Solv: ethanol (64-17-5); chloroform (67-66-3))
Boling Point	247.6±30.0 °C(Predicted)
Flash Point	103.6°C
Vapor Presure	0.0254mmHg at 25°C
pKa	7.78±0.20(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.548

1,7-Naphthyridine, 5,6,7,8-tetrahydro- - Introduction

5,6, 7,8-tetrahydro-[1,7] naphthyridine (abbreviated THN) is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
- THN is a colorless to pale yellow liquid with a special smell.
-It is flammable and can be dissolved in many organic solvents.

Use:
- THN is mainly used in the manufacture of drugs. It can be used as a synthetic intermediate for the synthesis of more complex organic compounds.
- THN has certain application potential in the medical field, such as as analgesics, anxiolytics and antidepressants.

Preparation Method:
- THN can be prepared by hydrogenation of naphthalene. A common method is to dissolve naphthalene in absolute ethanol, add an appropriate amount of catalyst (such as platinum catalyst), and carry out the reaction at an appropriate temperature and pressure.

Safety Information:
- THN requires safety during handling and storage. It is combustible and should be kept away from open flames and high temperature sources.
-Wear protective glasses and gloves when using to avoid contact with skin and eyes.
-When handling THN, it should be done in a well-ventilated place to avoid inhaling its vapor.
- THN needs to be stored in a sealed container, away from fire and oxidizing agents.

Last Update：2024-04-09 19:05:46